Background:   PROVOCATION (Prophylactic Intravenous Hydration for Contrast Agent Toxicity Prevention Study) is a randomized,  controlled, open-label, multi-center study evaluating the efficacy of two regimens of sodium bicarbonate compared with a prolonged infusion of sodium chloride in the prevention of contrast induced nephropathy.  Trial Registration No: NCT00130598 (    Link  Trial Status: Enrollment closed, manuscript published, ongoing data analysis  Enrolling Centers:  (click on images to enlarge) Core Study Team:  Recent Publication:
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Sodium chloride vs. sodium bicarbonate for the prevention of contrast medium-induced nephropathy: a randomized controlled trial. Klima T et al. Eur Heart J. 2012 Jan 19. C. Stelzig, MSc Home News Team Studies Publications Events Cooperations Contact